| SUTENT, an oral multi-kinase inhibitor, is the malate salt of sunitinib. Sunitinib malate is described chemically as Butanedioic acid, hydroxy-, (2S)-, compound with N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (1:1). The molecular formula is C22H27FN4O2 •C4H6O5 and the molecular weight is 532.6 Daltons.
The chemical structure of sunitinib malate is:
|
5-Fluoroisatin |
443-69-6 |
Sunitinib intermediate |
|
5-Fluorooxindole |
56341-41-4 |
Sunitinib intermediate |
|
N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-
1H- pyrrole-3-carboxamide |
|
Sunitinib intermediate |
|
N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-
1,2- dihydro-3H-indol-3-ylidene)methyl]-2,4-
dimethyl-1H- pyrrole-3- carboxamide |
341031-54-7 |
Sunitinib intermediate |
|
