|
4-Chloro-(2-pyridyl))-N-methylcarboxamide |
220000-87-3 |
Sorafinib intermediate |
|
1-Chloro-2-(trifluoromethyl)-4-isocyanatobenzene |
327-78-6 |
Sorafinib intermediate |
|
4-Chloro-6,7-Bis-(2-methoxyethoxy)-4(3H)
quinazoline |
284462-37-9 |
Sorafinib intermediate |
|
4-Chloropyridine-2-carbonyl chloride
Hydrochloride |
|
Sorafinib intermediate |
|
N-[4-Chloro-3-(trifluoromethyl)phenyl
]-({4-[2-(N-methyl-carbamoyl)(4-
pyridyloxy)]phenyl}amino)-carboxamide |
284461-73-0 |
Sorafinib intermediate |
multikinase inhibitor targeting several serine/threonine and receptor tyrosine kinases, is the tosylate salt of sorafenib.
Sorafenib tosylate has the chemical name 4-(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N 2-methylpyridine-2-carboxamide 4-methylbenzenesulfonate and its structural formula is:
Sorafenib tosylate is a white to yellowish or brownish solid with a molecular formula of C21H16ClF3N4O3 x C7H8O3S and a molecular weight of 637.0 g/mole. Sorafenib tosylate is practically insoluble in aqueous media, slightly soluble in ethanol and soluble in PEG 400.
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