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Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-ethyl-propoxy)-cyclohex-1-ene-1-carboxylate
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No:  32410322816
Product Name:  Pemetrexed Disodium
CAS No:  150399-23-8
 
 
Appearance:Almost-white or light yellow unfixed powder, smell-less, hygroscopic freely.
Empirical Formula: C20H19N5Na2O6   
 
Specification:
Solubility:Soluble in water very freely, in ethanol or chloroform or ethyl ether hardly
Specific optical rotation:+10°~ +13°
Absorption coefficient :The absorption coefficient---E(1%1cm) is 577-692 at 225nm wavelength.
Identification:
(1)The product appears flame reaction of sodium salt.
(2)UV: Max absorption at 225nm wavelength.
(3)IR: Meet the requirements
PH value:6.5~8.5
Clarity and color of solution:Meet the requirements
Related substance:
Max single impurity ≤0.5%
Total impurity ≤1.5%
Optical isomer:≤0.500%
Methanol:≤0.300%
Methyl chloride:≤0.060%
Chloroform:≤0.006%
Tetrahydrofuran:≤0.072%
Toluene:≤0.089%
Assay:≥99.50%, calculated on the anhydrous basis.
 
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